Bioinformatics tools for marine-derived chemotherapeutic drug discovery and designing

Arya Krishna, Sindura K P, Soni K B, Swapna Alex

Abstract


Cancer is a major menace to the modern world and better treatment opportunities are a need of the hour.  A wide range of therapies is used for combating cancer ranging from surgery to immunotherapy.  Phytochemicals have been used for their anti-cancer activities since ancient times. Marine organisms are also potential sources of drugs with anti-cancer activities even though they are underexplored when compared to terrestrial ecosystems. Bioinformatics tools have accelerated the drug discovery process as they can be used for high throughput screening of compounds. The present review gives a quick glimpse of the anti-cancer compounds derived from marine organisms and the different informatics tools that can be used for research on drugs for cancer.


Keywords


Drug development, Cancer, Protein database, Pathway database, Molecular databases, Anti-cancer compounds.

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References


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